Genetic Structure - Page 6
Gene Expression
Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Most genes contain the information needed to make functional molecules called proteins. The journey from gene to protein is complex and tightly controlled within each cell.
Gene expression consists of two major steps:
Transcription first, then Translation
Together, transcription and translation are known as gene expression. This drawing provides a graphic overview of the many steps involved in transcription and translation:
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(a) Within the nucleus of the cell (light blue), genes (DNA, dark blue) are transcribed into RNA. (b) This RNA molecule is then subject to posttranscriptional modification and control, resulting in a mature mRNA molecule (red) (c) It is then transported out of the nucleus and into the cytoplasm (peach), where it undergoes translation into a protein. mRNA molecules are translated by ribosomes (purple) that match the three-base codons of the mRNA molecule to the three-base anti-codons of the appropriate tRNA molecules. (d) These newly synthesized proteins (black) are often further modified, such as by binding to an effector molecule (orange), to become fully active. |
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Image Courtesy of National Center for Biotechnology Information |