Important research tools now exist to better understand DNA structure, gene function and the analysis of genetic interactions - such as how one gene tells another gene what to do.
It has long been recognized that cancer is the result of a cascade of genetic mutations that allow uncontrolled cell growth. Thus, to understand cancer research, it is necessary to become familiar with some very basic components of genetics.
The Five Basic Players
- Deoxyribonucleic acid (DNA)
- Genes
- Chromosomes
- Ribonucleic acid (RNA)
- Proteins
Deoxyribonucleic acid (DNA)
Lets start at the beginning. DNA is the building block of all information needed to form a living thing such as single cell organisms like bacteria, yeast and some viruses or multicellular organisms like humans, trees and starfish.
If you were to lay out, end to end, all the DNA from just one of your cells, the line would be over six feet long. You have roughly 100 trillion cells, so laid out all together the DNA in your body would easily stretch to the sun and back - nearly 100 times!
You're probably wondering how a huge DNA molecule can fit into a very tiny cell so small that you can't see it with the naked eye. Here's how: DNA is tightly packed much like a phone cord thats been twisted around and around itself. So, over six feet of DNA is compressed into only a few thousands of an inch.
DNA is a remarkably durable molecule, it can be stored in ice or in a fossilized bone for thousands of years. DNA can stay in one piece for as long as 100,000 years under the right conditions. This durability is why scientists can recover DNA from 14,000 year old mammoths.