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Understanding Tissue Issues
(Biospecimen) Donation

CISN Summary


Current research strategies are greatly enhanced by the contribution of tissue by patients - those with cancer and those without.

This is the only way science can make advances in "personalized" medicines so doctors can treat tumors based upon specific targets.

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The National Cancer Institute

The National Cancer Institute Office of Biorepositories and Biospecimen Research:

The Centers for Medicare & Medicaid Services (CMS)


Weining Tang et al, “DNA Extraction from Formalin-Fixed Paraffin-Embedded Tissue, Cold Spring Harbor Protocols, 2009.

Dry, S, “Who Owns Diagnostic Tissue Blocks?, Lab Medicine, February 2009, Volume 40, Number 2

Consensus Statement: Informed Consent for Genetic Research on Stored Tissue Samples, Journal of the American Medical Association, December 13, 1995

The Center for Disease Control (CDC) Website,

Sandusky, G, Dumaual, C, and Cheng L, “Human Tissues for Discovery Biomarker Pharmaceutical Research: The Experience of the Indiana University Simon Cancer Center – Lilly Research Labs Tissue/Fluid Biobanks”, Veterinary Pathology 2009 46:2

Compton, C, Ph.D, “Getting to Personalized Medicine: Taking Out the Garbage” Cancer October 15, 2007, Volume 110, Number 8

Sherman, ME, Figueroa, JD, Henry, JE “The Susan G Komen for the Cure Tissue Bank at the IU Simon Cancer Center: A Unique Resource for Defining the “Molecular Biology” of the Breast, Cancer Prevention Research, 2012;5:528-535.

Brothers, KB, Morrison, DR, Clayton, EW 2011. Two large-scale surveys on community attitudes toward an opt-out biobank. American Journal of Medical Genetics Part A 155;2982-2990

Langseth, H, Luostarinen, T, Bray, F, Dillner, J, “Ensuring quality in studies linking cancer registries” Acta Oncologica, 2010;49:368-377’’

Personalized Medicine
Recently Diagnosed
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“Content Developed September 1, 2012”


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