CISN - How Cancer is Studied - Epidemiology Research Scientists
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Epidemiology Research ScientistsEpidemiology researchers (called epidemiologists) study the distribution of diseases in the real world, and the factors that influence the occurrence of disease. Epidemiologists typically have specialized training in statistical methods, as well as health sciences. Epidemiologists rely on a number of other scientific disciplines, such as: biology (to better understand disease processes); geographic information science (to store data and map disease patterns), and social science disciplines (to better understand risk factors). An epidemiologist attempts to determine: Who - What - Where - When - How - Why
Populations as a whole, not the individual, are the focus of epidemiology research. Studies involving cancer risk, for example, cannot predict whether an individual with a certain exposure or genetic alteration will develop cancer, but they can estimate the likelihood that a certain proportion of people (e.g., one out of 100) will develop cancer. |
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To date, few universities offer epidemiology as a course of study at the undergraduate level. Many epidemiologists are physicians, or hold other postgraduate degrees including a Master of Public Health (MPH), and Master of Science or Epidemiology (MSc.). Doctorates epidemiologits may hold include the Doctor of Public Health (DrPH), Doctor of Pharmacy (PharmD), Doctor of Philosophy (PhD), Doctor of Science (ScD), or for clinically trained physicians, Doctor of Medicine (MD) and Doctor of Veterinary Medicine (DVM). As public health/health protection practitioners, epidemiologists work in a number of different settings. Some epidemiologists work 'in the field'; i.e., in the community, commonly in a public health/health protection service and are often at the forefront of investigating and combating disease outbreaks. Other epidemiologists work for non-profit organizations, universities, hospitals and larger government entities such as the Centers for Disease Control and Prevention (CDC) or the World Health Organization (WHO). We have included a glossary of terms imbedded at the end of this section since epidemiology uses very different terms from other research fields. Determining CauseAlthough epidemiology is sometimes viewed as a collection of statistical tools used to elucidate the associations of exposures to health outcomes, a major function of this science is that of discovering causal relationships. Cancer is not a single disease, but the generic name for more than 200 diseases, all having in common the uncontrolled reproduction of abnormal cells. Although scientists have only recently begun to understand the causes and growth patterns of cancer, there exists a large and growing body of evidence showing that daily choices about diet, physical activity, carcinogen exposures and weight management play a role in cancer risk. Epidemiologists use collected data and employ a broad range of biomedical and psychosocial theories in an iterative (each fact builds on the next) way to generate or expand theories, to test hypotheses, and to generate educated, informed decisions about which relationships are causal for a disease, and about exactly how they are causal. Epidemiologists Rothman and Greenland emphasize that the "one cause - one effect" understanding is a simplistic misbelief. Most outcomes, whether they be disease or death, are caused by a chain or web of events consisting of many component causes. For example, do cigarettes 'cause' lung cancer? The weight of the observational evidence showed that tobacco use was related to a large number of cancers. Epidemiologists published these findings. As people decided to stop smoking, the rates for these cancers started plummeting. Does this mean that epidemiologists understand the mechanism by which tobacco smoke produces cancer in humans? No they don't and actually, neither do basic researchers, although they have a myriad of hypotheses.
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